與風濕病相關的自體抗體
SLE全身性紅斑性狼瘡
dsDNA 30-90 %
Nucleosomes 40-70 %
Histones 50-80 %
U1-nRNP 15-40 %
Sm 5-30 %
SS-A (Ro) 20-60 %
SS-B (La) 10-20 %
Cyclin I (PCNA) 3 %
Ku 5-20 %
Ribosomal P 20-40 %
Cardiolipin、β2-GP1 5-10 %
Progressive Systemic Sclerosis (diffuse form)
自體抗體 盛行率
SSDNA 30-60 %
Fibrillar in (U3-nRNP) 5-10 %
PM-Scl 3 %
Sc1 -70 25-75 %
RNA Polymerase 4 %
7-2-RNP (To) Rare
NOR (NOR-90) Rare
Mixed Connective Tissue Disease
自體抗體 盛行率
U1-NRNP 95-100 %
SSDNA 20-50 %
Rheumatoid Arthritis
自體抗體 盛行率
Histone Rare
ssDNA 8%
Rheumatoid factor 65-95 %
CCP(Filaggrin eptopes) 80 %
Progressive Systemic Sclerosis (limited form)
自體抗體 盛行率
Centromere 80-95 %
Neonatal Lupus Erythematosus
自體抗體 盛行率
SS-A 100 %
Polymary Sjorgren' s Syndrome
自體抗體 盛行率
SS-A 40-95 %
SS-B 40-95 %
SSDNA 30-60 %
RANA 70 %
Salivary gland excretory ducts 40-60 %
Rheumatoid factors 60-80 %
Polymyositis and Dermatomytosi tis
自體抗體 盛行率
PM-Scl 8 %
Jo-1 25 - 35 %
Mi-2 5 %
Ku 30 - 55 %
ss-DNA 40 - 50 %
PL-7. PL-12 3-4 %
SRP Rare
Chronic Active Autoimmune Hepatitis
自體抗體 盛行率
Actin 40 - 90 %
ANA (lamins, SS-A and others) 30 - 40 %
Liver-Kidney microsomes (LKM-1) 7 %
Soluble liver Ag/ Liver-pancreas Ag (SLA-LP) 10-30 %
Liver membrane Ag (LMA) 35 -100 %
Liver-specific protein (LSP) 50 -100 %
M2 (pyruvate dehydrogenase) 5-20 %
M9 (glycogen phosphorylase) 10 %
Asialoglyprotein receptor protein 80 - 90 %
Primary Biliary Cirrhosis
自體抗體 盛行率
M2 (pyruvate dehydrogenase) 95 %
M9 (sulfite oxidase) Up to 55 %
M8 Up to 55 %
M9 35 - 85 %
Nuclear dots 30 %
Lamins 2 %
Medication-Induced Lupus
自體抗體 盛行率
Histones 95 %
Ss-DNA 80 %